Is it true that one of the second referee's specific responsibilities is to whistle a warning at 45 seconds and instruct the timer to sound the audio signal at 60 seconds to end the timeout?

The statement is accurate regarding the responsibilities of the second referee during a timeout. One of the key functions of the second referee is to manage the timing of timeouts effectively. By whistling a warning at 45 seconds, the second referee ensures that the team is aware that their timeout is nearing its end. This proactive communication helps maintain the flow of the game and prepares the teams to resume play promptly.

Additionally, instructing the timer to sound the audio signal at 60 seconds marks the definitive end of the timeout period. This helps to avoid any confusion over the duration and ensures that all players and coaches are aware that it is time to return to play. These responsibilities are essential for maintaining order and adherence to the rules during the match.